Table 1.

Comparison of D1 and D2 lymphadenectomy approaches in advanced gastric cancer [51,52,53,54,55,56,57,58].

Characteristics	D1 Lymphadenectomy	D2 Lymphadenectomy
Extent of lymph node dissection	Removal of perigastric lymph nodes (stations 1–6)	Removal of perigastric and extragastric lymph nodes (stations 1–12)
Number of retrieved lymph nodes	Average of 15–25	Average of 30–40
Operative time	Generally shorter (around 2–4 h)	Generally longer (around 4–6 h)
Postoperative complications	Lower risk of complications such as anastomotic leakage or pancreatic fistula Lower risk of delayed gastric emptying	Higher risk of complications such as anastomotic leakage or pancreatic fistula Higher risk of delayed gastric emptying Higher risk of intra-abdominal abscess Higher risk of lymphatic leakage Higher risk of bleeding Higher risk of wound infection

(Table 1 provides a concise summary of the key characteristics and differences between D1 and D2 lymphadenectomy approaches in terms of the extent of lymph node dissection, number of retrieved lymph nodes, operative time, and postoperative complications) [51,52,53,54,55,56,57,58].