Table 6.

A comparison of the clinical outcomes of XEN45 and trabeculectomy. Adapted from Chen et al. [12], Wang et al. [107], and Sheybani et al. [108].

Study	XEN		Trabeculectomy		MD (95% CI) between Surgeries 1
	MD	SD	MD	SD
Parra et al. [48]	−4.34	9.3	−7.73	8.97	0.37 (0.01 to 0.73)
Teus et al. [58]
Chen et al. [12]	−7.2	9.2	−10.5	9.2	−3.30 (−6.08 to −0.52)
Wang et al. [107]	−8.8	5.2	−8.5	5.3	−0.06 (−0.86 to 0.75)
Olgun et al. [65]	−11	6.4	−16	9.7	0.63 (0.17 to 1.09)
Wagner et al. [72]	−8.5	5.3	−8.8	5.2	−0.30 (−4.51 to 3.91)
Wanichwecharungruang and Ratprasatporn [84]	−7	3.8	−10	5	−3.0 (−4.65 to −1.35)
Sheybani et al. [108]	−8.7 *	5	−10.8	4.7	−2.1 (−3.9 to −0.3)
Schlenker et al. [109]	−11	0.74	−11	7.29	0.0 (−0.21 to 0.21)
Sacchi et al. [110]	−13.38	2.76	−15.17	3.2	0.59 (0.04 to 1.15)
Olgun et al. [111]	−11	6.4	−16	9.7	−5.00 (−8.86 to −1.14)

¹ Random effect model. * Extracted directly from the study. NP: not provided.