Table 3.
Essential information about methods of pain relief explored in the reviewed studies.
| Study | Tools Used to Collect Pain Information from Patients | Findings | Ref. |
|---|---|---|---|
| Cepeda et al. | CPPR and PRPPR | Pain decreased from initial pain following analgesic administration. | [56] |
| Musshoff et al. | Hair analysis | Hair analysis can be a valuable and supplementary method for isolating patients who take opioid analgesics for pain relief. | [57] |
| Dalal and Bruera | Personalized therapy and education of patient/family in decision-making | Cancer-related pain is a multidimensional construct resulting from a complicated combination of physiological, socio-cultural, psychological, behavioral, sensory, and cognitive factors. | [58] |
| Sarzi-Puttini et al. | Selecting an effective, suitable, personalized analgesic prescription for individuals with chronic pain is feasible | Personalized analgesic prescription will improve compliance, general functioning, and QoL. | [59] |
| Petersen et al. | Prepared an item bank of 16 pain-measurement items appropriate for CAT | The pain CAT is now available for “experimental” uses by the EORTC. | [61] |
| Balducci and Dolan | Investigated palliative care for disease in elderly patients | Target planning, symptom control, and caregiver attention are the three foundations of effective palliative care. | [62] |
| Bhatnagar and Gupta | Integrating cancer pain and symptom management into present pain management | Simultaneously collect information and develop guidelines and suggestions for accurate symptom management across a wide range of patients and diseases to provide a personalized strategy for patient care. | [63] |
| Arthur et al. | Relationship between ECS-CP characteristics and pain treatment results among outpatients | Neuropathy was a poor predictive factor in the treatment of advanced cancer pain. | [64] |
| Colvin | Repurposing drugs such as metformin | During oncological treatment, any new therapies adopted must not conflict with the tumoricidal impacts of chemotherapy. | [66] |
| Vimalnath et al. | Production and investigation of Ce-141 as an effective theragnostic agent for metastatic skeletal lesions | Potential value of 141Ce-DOTMP as a theragnostic component proved for tailored patient treatment of cancer patients. | [67] |
| Sica et al. | Studied the efficiency of the intrathecal pump in 140 patients | Intrathecal is safer than systemic opioids, which frequently require greater dosages to be efficient leading to the probable major side effects. | [68] |
| Cuomo et al. | Trolley analgesic model | The employment of personalized therapies with dynamic multimodal methods for pain management found. | [70] |
| LeBaron et al. | BE-SI-C | BE-SI-C has the ability to track and predict pain while also improving self-efficacy, safety, communication, and QoL in cancer patients. | [72] |
| Oldenmenger et al. | Examined nine BAT questions, such as “How often do you get breakthrough pain?” | BAT is a legitimate and precise questionnaire that may be used in everyday practice to measure breakthrough pain in Dutch cancer patients. | [74] |
| Ben-Arye et al. | IO therapy in 815 eligible patients receiving cancer treatment in adjuvant, neo-adjuvant, and palliative care settings. | An initial consultation with an integrative clinician and follow-up visits and receiving adjuvant and neo-adjuvant were the benefits. | [76] |
| Mao et al. | Electroacupuncture or auricular acupuncture | Electroacupuncture and auricular acupuncture reduced pain. | [77] |
| Batistaki et al. | Investigated the relationship between BTcP, background cancer pain, and analgesic therapy | A multimodal analgesic approach is proposed. | [81] |
| Masukawa et al. | Established machine learning models in CPM | They predicted social pain, spiritual pain, and severe signs in terminally suffering cancer patients using text data from electronic healthcare records. | [82] |
| Reddy et al. | Transition from opioids to levorphanol utilizing an ORR of 8.5 | Levorphanol was well tolerated and linked to better pain and symptom management. | [84] |
| Aziz and Cascella | Peripheral neurolytic blocks | Some forms of painful diseases must be handled by administration of less-invasive analgesic procedures. | [85] |
| Dalal et al. | Utilized level of pain reduction on a scale from 0 to 10 and median PPG | Regular PPG recording may help with personalized pain management. | [86] |
Abbreviation: ref: reference; CPPR: calculated percentage of pain reduction; PRPPR: patient-reported percentage of pain reduction; QoL: quality of Life; CAT: computerized adaptive testing; EORTC: European Organization for Research and Treatment of Cancer; ECS-Cp: Edmonton Classification System for Cancer Pain; BE-SI-C: Behavioral and Environmental Sensing and Intervention for Cancer; BAT: Breakthrough Pain Assessment Tool: IO: integrative oncology; BTcP: breakthrough cancer pain; RR: opioid rotation ratio; PPG: personalized pain goal.