Table 3.
LCN2, sTfR, and EPO Levels in Patients with and without Anemia
| Parameters | Patients | p value | |
|---|---|---|---|
| With Anemia (n = 51) | Without Anemia (n = 184) | ||
| Age (year) | 61.2 ± 7.4 | 59.6 ± 7.8 | 0.192 |
| Sex (male; n, %) | 27 (52.9) | 105 (57.1) | 0.593 |
| LCN2 (ng/mL) | 195.8 (97.2–278.5) | 142.0 (63.5–205.3) | < 0.001 |
| cLCN2 (ng/mL) | 176.3 (82.1–214.6) | 123.2 (56.4–172.8) | < 0.001 |
| EPO (IU/L) | 8.9 (3.4–15.1) | 10.7 (4.5–18.9) | 0.145 |
| sTfR (mg/L) | 3.61 ± 2.43 | 2.18 ± 1.67 | < 0.001 |
| Serum iron (µg/dL) | 24.5 ± 16.2 | 43.2 ± 21.5 | < 0.001 |
| Estimated CrCl (mL/min) | 67.2 ± 7.4 | 71.5 ± 8.9 | 0.002 |
| hsCRP (mg/dL) | 0.29 (0.24–2.35) | 0.24 (0.19–2.17) | 0.417 |
Notes: Data are expressed as mean ± SD, median (IQR), or frequency (%).
Abbreviations: LCN2, lipocalin-2; cLCN2, corrected lipocalin-2; EPO, erythropoietin; sTfR, soluble transferrin receptor; CrCl, creatinine clearance; hsCRP, high-sensitivity C-reactive protein.