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. 2023 Aug 12;21(8):447. doi: 10.3390/md21080447

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Effect of epi-oxyzoanthamine (ZV-AI) on DNCB-induced atopic dermatitis in dorsal skin (upper panel). Effect of epi-oxyzoanthamine on DNCB-induced atopic dermatitis in ears. H and E staining of ear tissue sections. Red arrows point to the epidermis (lower panel). (B) Upper panel shows the inhibitory effect of the inflammatory response on the ear. Lower panel shows statistical results of ear inflammation thickness. ## p < 0.01 compared with the no-treatment group; * p < 0.05 and ** p < 0.01 compared with the DNCB-induced group.

(A) Effect of epi-oxyzoanthamine (ZV-AI) on DNCB-induced atopic dermatitis in dorsal skin (upper panel). Effect of epi-oxyzoanthamine on DNCB-induced atopic dermatitis in ears. H and E staining of ear tissue sections. Red arrows point to the epidermis (lower panel). (B) Upper panel shows the inhibitory effect of the inflammatory response on the ear. Lower panel shows statistical results of ear inflammation thickness. ## p < 0.01 compared with the no-treatment group; * p < 0.05 and ** p < 0.01 compared with the DNCB-induced group.