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(A) Toluidine blue staining of the dorsal skin; scale bar: 50 μm (upper panel) and statistical analysis of the mast cells. The red arrow points to the mast cells. (B) Effect of epi-oxyzoanthamine on spleen weight. (C) Analysis of the effect of the change in the number of scratches in BALB/c mice with an atopic-dermatitis-like phenotype. ## p < 0.01 compared with the no-treatment group; * p < 0.05 and ** p < 0.01 compared with the DNCB-induced group.
