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. 2023 Aug 25;18(8):e0290428. doi: 10.1371/journal.pone.0290428

Table 1. Comparison of characteristics between patients whose disease progressed prior to and after 90 days.

Characteristics PD<90 Days PD >90 Days
Number of patients 7 11
Mean age (years) at diagnosis (range) 7.6 (5–10) 7.0 (3–11)
PFS (range) 59 (14–82) 185 (97–489)
MST (range) 81 (18–292) 737 (300–989)
Breed N (%) N (%)
Mixed breed 1 (14) 7 (64)
Pitbull 1 (14) 2 (18)
Mastiff 1 (14) 0
Yorkshire Terrier 1 (14) 0
Bulldog 1 (14) 0
Cattle dog 1 (14) 0
Scottish Terrier 1 (14) 0
German Shepherd 0 1 (9)
Pug 1 (9)
Gender N (%)  N (%) 
Castrated male 3 (43) 4 (36)
Spayed female 3 (43) 6 (55)
Intact male 1 (14) 0
Intact female 0 1 (9)
Stage N (%)  N (%) 
IIIa 4 (57) 6 (55)
IIIb 0 1 (9)
IVa 2 (29) 3 (27)
IVb 1 (14) 1 (9)
Va 0 0
Trial arm N (%)  N (%) 
KPT-9274 3 (43) 4 (36)
TAK-981 2 (29) 3 (27)
RV1001 2 (29) 4 (36)

PD, progressive disease; PFS, progression free survival; MST, median survival time. Age is represented in years as a mean (range). PFS and MST are represented in days as a median (range). Breed, gender, stage, and trial arm are shown as number (percent).