Table 1. Comparison of characteristics between patients whose disease progressed prior to and after 90 days.
Characteristics | PD<90 Days | PD >90 Days |
---|---|---|
Number of patients | 7 | 11 |
Mean age (years) at diagnosis (range) | 7.6 (5–10) | 7.0 (3–11) |
PFS (range) | 59 (14–82) | 185 (97–489) |
MST (range) | 81 (18–292) | 737 (300–989) |
Breed | N (%) | N (%) |
Mixed breed | 1 (14) | 7 (64) |
Pitbull | 1 (14) | 2 (18) |
Mastiff | 1 (14) | 0 |
Yorkshire Terrier | 1 (14) | 0 |
Bulldog | 1 (14) | 0 |
Cattle dog | 1 (14) | 0 |
Scottish Terrier | 1 (14) | 0 |
German Shepherd | 0 | 1 (9) |
Pug | 1 (9) | |
Gender | N (%) | N (%) |
Castrated male | 3 (43) | 4 (36) |
Spayed female | 3 (43) | 6 (55) |
Intact male | 1 (14) | 0 |
Intact female | 0 | 1 (9) |
Stage | N (%) | N (%) |
IIIa | 4 (57) | 6 (55) |
IIIb | 0 | 1 (9) |
IVa | 2 (29) | 3 (27) |
IVb | 1 (14) | 1 (9) |
Va | 0 | 0 |
Trial arm | N (%) | N (%) |
KPT-9274 | 3 (43) | 4 (36) |
TAK-981 | 2 (29) | 3 (27) |
RV1001 | 2 (29) | 4 (36) |
PD, progressive disease; PFS, progression free survival; MST, median survival time. Age is represented in years as a mean (range). PFS and MST are represented in days as a median (range). Breed, gender, stage, and trial arm are shown as number (percent).