Table 2. Treatment protocols for arms in current study.
Arm | Treatment Protocol |
---|---|
KPT-9274 | Anti-CD20 20mg/kg IV q3 weeks for 4 doses |
Doxorubicin 25mg/m2 IV q3 weeks for 4 doses | |
KPT-9274 4mg/kg PO q3 weeks for 4 doses | |
TAK-981 | Anti-CD20 10-20mg/kg IV q1 week for 4 doses |
Doxorubicin 25mg/m2 IV once on day 0 | |
TAK-981 2.5-3mg/kg IV q1 week for 4 doses | |
RV1001 | Anti-CD20 10-20mg/kg IV q3 weeks for 4 doses |
Doxorubicin 20-25mg/m2 IV q3 weeks for 4 doses | |
RV1001 10mg/kg PO q24h 4 days on, 3 days off, weekly (12 weeks total or until disease progression) |