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. 2023 Aug 3;59(8):1413. doi: 10.3390/medicina59081413

Table 2.

Principal elements of the studies that formed part of the present systematic analysis. * Statistically significant correlation.

Author Year Nationality Number of Case vs. Control Age Diagnostic Tool of Mucositis Correlation of Mucositis Grade between Laser and Placebo Significance of Study
Vitale [25] 2017 Italy 16 patients:
8 laser group
8 placebo
12.4 yrs WHO Vas e WHO
Laser Group:
T0 3.38
T1 3 days 2.73
T2 7 days 1.50
T3 11 days 0.38
Placebo:
T0 3.38
T1 3 days 3.38
T2 7 days 2.38
T3 11 days 1.88
(p < 0.05) *
Laser is an excellent aid for the treatment of mucositis
Kuhn [26] 2008 Brazil 21 patients
9 laser group
12 placebo
8.2 yrs WHO Laser Group: T0 3.0
T1 3 days 2.3
T2 7 days 0.73
T3 11 days 0
Placebo:
T0 3.1
T1 3 days 2.8
T2 7 days 1.8
T3 11 days 0.54
p = 0.0029 *
Laser is an excellent aid for the treatment of mucositis
Khouri [27] 2009 Brazil 22 patients:
12 laser
10 control
32.7 yrs WHO Laser Group:
T0:3.0
T1 7 days 1.74
Placebo:
T0 3.0
T2 7 days 2.45
p = 0.001 *
Laser is an excellent aid for the treatment of mucositis