Table 3.
The IC90 values (μM) of antibacterial bioassays of compounds 1–10 a.
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | TC | OT | LF | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Streptococcus parauberis FP KSP28 | 0.3 | 0.5 | 2.7 | 0.1 | 4.9 | 1.1 | 0.5 | 8.9 | 4.4 | 1.0 | 6.3 | 3.1 | 3.1 |
| Phoyobacterium damselae FP2244 | 9.1 | 4.2 | 11.0 | 8.5 | 9.8 | 9.2 | 2.2 | 2.2 | 4.4 | 2.0 | 0.1 | 0.1 | 0.1 |
| Streptococcus parauberis SPOF3K | 9.1 | 4.2 | 11.0 | 8.5 | 9.8 | 4.6 | 2.2 | 2.2 | 4.4 | 2.0 | >50.0 | 25.0 | 3.1 |
| Aeromonas salmonicida AS42 | - b | - | - | - | - | - | 8.8 | - | - | - | 12.7 | 0.8 | 0.8 |
| Enterococcus faecium G1 | - | - | - | - | - | - | 8.8 | - | - | 8.0 | 0.2 | 0.4 | >100.0 |
| Enterococcus faecium G4 | - | - | - | - | - | - | - | - | - | 4.0 | 0.4 | 0.4 | >100.0 |
| Enterococcus faecium G7 | - | 16.8 | - | - | - | 18.3 | 8.8 | 8.9 | 4.4 | 8.0 | 0.2 | 0.2 | >100.0 |
| Enterococcus faecium G8 | - | - | - | - | - | - | - | - | - | 8.0 | 0.2 | 0.1 | >100.0 |
| Streptococcus agalactiae WR10 | 18.1 | 8.4 | 22.0 | 17.0 | - | - | 4.4 | 4.4 | - | 4.0 | 1.6 | 1.6 | 6.3 |
a Tetracycline hydrochloride (TC), oxytetracycline hydrochloride (OT), levofloxacin hydrochloride (LF) were used as positive controls. b ‘-’ indicated they were not subjected to the antibacterial rescreening experiments since their inhibition rates against these bacteria were <90% in the preliminary antibacterial bioassays.