Table 3.
Antimicrobial Drug | AmpC-Producing N = 142 n (%) |
AmpC-Non-Producing N = 91 n (%) |
p | ESBL-Producing N = 27 n (%) |
ESBL-Non-Producing N = 206 n (%) |
p | KPC-Producing N = 179 n (%) |
KPC-Non-Producing N = 54 n (%) |
p |
---|---|---|---|---|---|---|---|---|---|
Ampicillin/sulbactam | 117 (82.4) | 83 (91.2) | 0.600 | 19 (70.4) | 181 (87.9) | 0.014 | 154 (86.0) | 46 (85.2) | 0.875 |
Piperacillin/tazobactam | 139 (97.9) | 91 (100.0) | 0.163 | 26 (96.3) | 204 (99.0) | 0.236 | 179 (100.0) | 51 (94.4) | 0.012 |
Ceftazidime | 141 (99.3) | 90 (98.9) | 0.750 | 26 (96.3) | 205 (99.5) | 0.219 | 178 (99.4) | 53 (98.1) | 0.411 |
Cefepime | 135 (95.1) | 89 (97.8) | 0.291 | 24 (88.9) | 200 (97.1) | 0.219 | 173 (96.6) | 51 (94.4) | 0.461 |
Imipenem | 138 (97.2) | 91 (100.0) | 0.106 | 26 (96.3) | 203 (98.5) | 0.391 | 178 (99.4) | 51 (94.4) | 0.040 |
Meropenem | 138 (97.2) | 91 (100.0) | 0.106 | 26 (96.3) | 203 (98.5) | 0.391 | 178 (99.4) | 51 (94.4) | 0.040 |
Ciprofloxacin | 142 (100.0) | 91 (100.0) | – | 27 (100.0) | 206 (100.0) | – | 179 (100.0) | 54 (100.0) | – |
Gentamicin | 113 (79.6) | 87 (95.6) | <0.001 | 21 (77.8) | 179 (86.9) | 0.201 | 156 (87.2) | 44 (81.5) | 0.295 |
Tobramycin | 128 (90.1) | 89 (97.8) | 0.031 | 27 (100.0) | 190 (92.2) | 0.133 | 165 (92.2) | 52 (96.3) | 0.294 |
Amikacin | 107 (75.4) | 85 (93.4) | <0.001 | 20 (74.1) | 172 (83.5) | 0.279 | 151 (84.4) | 41 (75.9) | 0.159 |
Tigecycline | 122 (85.9) | 57 (62.6) | <0.001 | 16 (59.3) | 163 (79.1) | 0.021 | 148 (82.7) | 31 (57.4) | <0.001 |
Tetracycline | 129 (90.8) | 55 (60.4) | <0.001 | 21 (77.8) | 163 (79.1) | 0.872 | 152 (84.9) | 32 (59.3) | <0.001 |
Doxycycline | 122 (85.9) | 19 (20.9) | <0.001 | 16 (59.3) | 125 (60.7) | 0.887 | 119 (66.5) | 22 (40.7) | 0.001 |
Trimethoprim/ Sulfamethoxazole |
103 (72.5) | 90 (98.9) | <0.001 | 22 (81.5) | 171 (83.0) | 0.790 | 143 (79.9) | 50 (92.6) | 0.038 |