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Specnuezhenide (SPN) treatment improved gut microbiota disbalance. (A) Principal correlation coefficient analysis (PCoA) analysis of gut microbiota at operational taxonomic units (OTUSA) level based on Bray−Curtis. (B) Shared and unique OTUs among the different groups. (C) The predicted functional metabolic pathways. (D) The relative abundance of bile salt hydrolase (BSH) related phylum (n = 5). Data are expressed as mean ± SD. * p < 0.05 compared with the MOD group.
