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In vitro permeation profiles of Metsal™ Cream applied on different skin membranes with 6% Brij™ O20 as receptor phase: (a) Cumulative amount versus time (Mean ± SEM n = 3) of methyl salicylate; (b) Cumulative amount versus time (Mean ± SEM n = 3) of salicylic acid; (c) Total amount of the actives permeated (Mean ± SEM n = 3).
