Table 3. False-positive report probability analysis for significant findings derived from TRMT61B rs4563180 and hepatoblastoma risk.
Genotype | OR (95% CI) | P a | Statistical power b | Prior probability | ||||
0.25 | 0.1 | 0.01 | 0.001 | 0.0001 | ||||
GC vs. GG | 0.65 (0.49-0.85) | 0.002 | 0.411 | 0.014 | 0.040 | 0.314 | 0.822 | 0.979 |
GC/CC vs. GG | 0.66 (0.51-0.85) | 0.002 | 0.450 | 0.011 | 0.033 | 0.272 | 0.791 | 0.974 |
<17 months | 0.61 (0.43-0.88) | 0.008 | 0.326 | 0.072 | 0.188 | 0.719 | 0.963 | 0.996 |
Female | 0.57 (0.38-0.86) | 0.008 | 0.230 | 0.092 | 0.234 | 0.770 | 0.971 | 0.997 |
Stage I+II | 0.66 (0.46-0.93) | 0.018 | 0.459 | 0.107 | 0.265 | 0.799 | 0.976 | 0.998 |
Stage III+IV | 0.55 (0.34-0.88) | 0.012 | 0.210 | 0.148 | 0.343 | 0.852 | 0.983 | 0.998 |
OR, odds ratio; CI, confidence interval.
aChi-square test was used to calculate the genotype frequency distributions.
bStatistical power was calculated using the number of observations in each subgroup and the corresponding ORs and P values in this table.