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. 2023 Aug 1;15(15):7583–7592. doi: 10.18632/aging.204926

Table 3. False-positive report probability analysis for significant findings derived from TRMT61B rs4563180 and hepatoblastoma risk.

Genotype OR (95% CI) P a Statistical power b Prior probability
0.25 0.1 0.01 0.001 0.0001
GC vs. GG 0.65 (0.49-0.85) 0.002 0.411 0.014 0.040 0.314 0.822 0.979
GC/CC vs. GG 0.66 (0.51-0.85) 0.002 0.450 0.011 0.033 0.272 0.791 0.974
<17 months 0.61 (0.43-0.88) 0.008 0.326 0.072 0.188 0.719 0.963 0.996
Female 0.57 (0.38-0.86) 0.008 0.230 0.092 0.234 0.770 0.971 0.997
Stage I+II 0.66 (0.46-0.93) 0.018 0.459 0.107 0.265 0.799 0.976 0.998
Stage III+IV 0.55 (0.34-0.88) 0.012 0.210 0.148 0.343 0.852 0.983 0.998

OR, odds ratio; CI, confidence interval.

aChi-square test was used to calculate the genotype frequency distributions.

bStatistical power was calculated using the number of observations in each subgroup and the corresponding ORs and P values in this table.