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Ferroptosis induced pathological changes in DM rats. The mRNA expression of ferroptosis related indicators of renal tissues (A–D). Immunohistochemical staining (E, 200× magnification) and semi-quantification analyses (F) of Col-I and Col-III in renal tissues of each group. The concentration of oxidant related indexes in renal tissues was measured (G–J). *P < 0.05, **P < 0.01 vs. normal group, #P < 0.05, ##P < 0.01 vs. model group.
