Figure 2.

Emodin attenuated DM related renal injury by inhibiting ferroptosis. The blood glucose levels and body weight were monitored at different intervention time (A, B). The measurement of renal function related indicators (C–F). HE and Masson staining (G) 200× magnification) as well as semi-quantitative analysis of glomerular area (H–J) of renal tissues in each group. The occurrence ferroptosis aggravated the progression of DN (K). ^*P < 0.05, ^**P < 0.01 vs. normal group, ^#P < 0.05, ^##P < 0.01 vs. model group.