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Emodin inhibited the deletion of Nrf2 induced ferroptosis. The expression level as well as semi-quantitative analysis of Nrf2 protein (A, B). The mRNA expression of Nrf2 (C). The expression levels as well as semi-quantitative analysis of ferroptosis indicators were measured in Si-Nrf2 cells with or without treatment (D, E). The changes in concentrations of iron and MDA were calculated (F, G). *P < 0.05, **P < 0.01 vs. Si-Nrf2 group, #P < 0.05, ##P < 0.01 vs. DM group.
