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. 2023 Aug 7;15(15):7673–7688. doi: 10.18632/aging.204933

Figure 6.

Figure 6

The RSL-3 induced cellular ferroptosis was suppressed by the treatment of Emodin. Different dose of RSL-3 was used to treat HK-2 cells exposed to culture medium containing 5.5 mmol/L glucose for 24 h (A). The mRNA expression of ferroptosis related indicators (B–F). The expression levels as well as semi-quantitative analysis of ferroptosis related proteins in RSL-3 group with or without Emodin treatment (G, H). The concentration of MDA and iron in RSL-3 group with or without Emodin treatment (I, J). *P < 0.05, **P < 0.01 vs. Ctrl group, #P < 0.05, ##P < 0.01 vs. RSL-3 group.