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. 2023 Mar 28;30(7-8):641–648. doi: 10.1038/s41434-023-00398-x

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© The Author(s) 2023

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Fig. 1 — AAV vectors were prepared in large-scale and harvested from the culture supernatant. Large amounts of AAV vectors were separated and fractionated by ultracentrifugation in a zonal rotor with serial (#Z1) or 2-step (#Z2–7) cesium chloride (CsCl) density-gradient. Each fraction was analyzed to measure the RI.