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. 2023 Aug 10;24(9):1540–1551. doi: 10.1038/s41590-023-01588-w

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© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — a) Relationship between minor allele frequency (MAF), pQTL effect size and proportion of variance explained (2MAF(1-MAF)Effect²), for 227 conditionally independent pQTLs (red=cis, blue=trans). b) Proportion of variance explained (PVE) by the conditionally independent variants associated with each protein. Proteins are annotated using the gene symbol of their encoding genes. Protein names are coloured in red if over 80% of samples have levels below the lower limit of detection in the INTERVAL dataset.