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. 2023 Aug 10;24(9):1540–1551. doi: 10.1038/s41590-023-01588-w

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© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — Comparison of effect sizes between pQTLs from the discovery pQTL meta-analysis (n = 14,824) and the ARISTOTLE cohort (n = 1,585). Each point represents a genetic variant that was a significant pQTL in the discovery meta-analysis. Effect size = standard deviation (sd) increase in protein per allele. 174 of 180 genetic variants were available for testing in the ARISTOTLE data. Red= cis, Blue= trans.