Table 1.

Health economic parameters.

Item	Assumption
Geographical presentation	World Bank income groups (HIC, UMIC, LMIC, LIC)
Vaccine doses	3 doses
Vaccination strategies	Routine vaccination at birth or 5 years of age
Cost per fully vaccinated person	$0–$300
Discounting	3% discounting for costs and health outcomes (default); 3% discounting for costs and 0% discounting for health outcomes (sensitivity analysis)
Wastage factor during vaccination campaigns	10% (default); 5% and 20% (sensitivity analysis)
Economic burden	Point estimates (default); 95% Confidence Intervals (sensitivity analysis); societal perspective
Cost-effectiveness threshold	1 x GDP per capita (default); health opportunity costs (health care system threshold)
Time period	Lifetime impact among 30 cohorts from the year of vaccine introduction
Vaccination scenarios	Scenario 1 - vaccine adoption year (country-specific), coverage rate (country-specific Hib3), full efficacy for 10 years
	Scenario 2 - vaccine adoption year (country-specific), coverage rate (country-specific Hib3), linear waning over 20 years
	Scenario 3 - vaccine adoption year (2022), coverage rate (50%), full efficacy for 10 years
	Scenario 4 - vaccine adoption year (2022), coverage rate (50%), linear waning over 20 years
	Scenario 5 - vaccine adoption year (country-specific), coverage rate (50%), full efficacy for 10 years
	Scenario 6 - vaccine adoption year (country-specific), coverage rate (50%), linear waning over 20 years