Table 1.
AFO-202 vs AFO-202+N-163 Beta glucans in healthy volunteers; results in a nutshell
| Beneficial effect | Biomarker | Outcome | Effective compound | P Value significance |
|---|---|---|---|---|
| Immune enhancement | Monocyte | Increase | AFO-202 | <0.05 |
| Eosinophils | AFO-202 | <0.05 | ||
| CRP | AFO-202 | |||
| IL-7 | AFO-202 | <0.05 | ||
| IL8 | AFO-202 | <0.05 | ||
| Immmunomodulation | IgA | Increase | AFO-202 +N-163 | <0.01 |
| IL-2 | AFO-202 +N-163 | <0.05 | ||
| LCR | AFO-202 +N-163 | |||
| LeCR | AFO-202 +N-163 | |||
| NLR | Decrease | AFO-202 +N-163 | <0.05 | |
| Metabolic regulation | HbA1c | Decrease | AFO-202 | <0.05 |
| Glycated Albumin | AFO-202 | <0.05 | ||
| T-Cho | AFO-202 +N-163 | <0.05 | ||
| LDL-Cho | AFO-202 +N-163 | <0.01 | ||
| Coagulopathy prevention | D-Dimer | Decrease | AFO-202 | <0.05 |
| Ferritin | AFO-202 +N-163 | |||
| Fibrinogen | AFO-202 +N-163 | |||
| Galectin-3 | AFO-202 +N-163 | |||
| CD11b | Increase | AFO-202 +N-163 |
Abbreviations: CRP- C-reactive protein; IL-Interleukin; Ig-Immunoglobin; LCR-Lymphocyte to C-reactive protein ratio; NLR- Neutrophil to Lymphocyte ratio; LeCR-Leukocyte to C-reactive protein ratio; LDL-Low density lipoprotein