Fig. 2.

PCRCP treatment prevents obesity and metabolic abnormalities in mice fed with HFD. (A) Schematic diagram of experiment. Animals were administered with Chow or HFD feeding, and orally given H₂O or 60 mg/kg/d PCRCP for four weeks. (B) The initial and final body weights of mice. (C) Representative photographs of gonadal adipose tissue of mice. (D-F) Visceral fat pad weights (gonadal, inguinal and perirenal white adipose tissues). (G) Average daily energy intake of mice. (H) Liver weight. (I) The level of fasting glucose. (J, K) Glucose tolerance and the area under curve. (L-P) The plasma levels of TG, CHO, LDL-C, ALT and AST of mice. (Q) Representative images of H&E staining for liver (scale bars, 200 μm) and gWAT (scale bars, 100 μm). Data are represented as the mean ± s.e.m. (n = 5–7). Statistical analysis was conducted by using one-way ANOVA followed by multiple comparisons, and ns means no statistical significance.