FIG. 1.

Schematic experimental description. (A) Acceleration-deceleration injury illustration. During the acceleration movement the brain tissue is compressed inside the skull and then put under tension in the following deceleration movement (B) Cellular response to TBI during acceleration and deceleration. Blue neurons, cyan: astrocytes, yellow: microglia cells, green: pericyte, red: endothelial cells. (C) The DTL system allows, by controlling the movement of the magnets, to bend the magnetic hydrogel, which causes a tension and compression effect on the cell. DTL, dynamic tissue-loading.