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. 2023 Aug 18;15(8):2157. doi: 10.3390/pharmaceutics15082157

Figure 6.

Figure 6

Biodistribution of free DiR solution, DiR-RL, and DiR-RL-Gel in vivo. (A) In vivo fluorescence images of keloid-bearing nude mice treated with DiR solution, DiR-RL, and DiR-RL-Gel. Images were taken at 2, 4, 6, 8, and 24 h after injection. (B) The fluorescence images of the excised keloids and major organs at 24 h after injection (n = 3, means ± SD). (C) The quantitative ROI analysis of the excised keloids and major organs at 24 h after injection (n = 3, means ± SD), # p < 0.05 and ### p < 0.001.