Table 5.

Downregulated pathways after vitamin D substitution.

Name of the Pathway	ES	NES	p-Value	FDR q-Value
Biocarta—FCεRI	0.90	1.88	<0.001	<0.001
GO—Activation of innate immune response	0.71	1.87	<0.001	<0.001
Hallmark—Complement	0.70	1.84	<0.001	<0.001
GO—Interferon Gamma response	0.68	1.78	<0.001	<0.001
GO—Regulation of interferon beta production	0.80	1.71	<0.001	0.002
GO—Positive regulation of interferon beta production	0.86	1.70	<0.001	0.002
GO—Leukocyte chemotaxis	0.67	1.64	<0.001	0.013
GO—Positive regulation of interferon alpha production	0.89	1.59	0.002	0.032
Hallmark—IL6/JAK/STAT3 signaling	0.66	1.58	<0.001	0.032
GO—Activation of immune response	0.57	1.57	<0.001	0.032
GO—Response to vitamin D	0.77	1.57	0.012	0.031

Abbreviations: ES: Enrichment Score, NES: Normalized Enrichment Score, FDR: false discovery rate, GO: Gene Ontology.