. 2023 Aug 14;12(16):2944. doi: 10.3390/plants12162944

Table 1.

In Vitro α-amylase inhibition properties reported from various plant extracts.

Name of Plants	Used Extract/Fraction/Parts	IC₅₀	IC₅₀ (Control) (Acarbose)	Ref.
Argania spinosa	Roasted seeds oil	2.17 ± 0.24 mg/mL	0.41 ± 0.015 mg/mL	[63]
Argania spinosa	Unroasted seeds oil	0.78 ± 0.16 mg/mL	0.41 ± 0.015 mg/mL	[63]
Melicope glabra (Blume) T. G. Hartley	Chloroform extracts (leaves)	303.64 ± 10.10 μg/mL	188.6 ± 14.31 μg/mL	[64]
Aloe megalacantha Baker	Leaf latex	74.76 ± 1.98 μg/mL	16.49 ± 1.91 μg/mL	[65]
Aloe monticola Reynolds		78.10 ± 1.88 μg/mL	16.49 ± 1.91 μg/mL	[65]
Hedychium coronarium Koen	Ethyl acetate fraction (rhizomes)	58.15 ± 1.23 μg/mL	-	[66]
Cichorium endivia	Hydrophilic fraction (extracted from leaves with ethanol/water)	9.96 μg/mL	10.00 μg/mL	[67]
Brown rice	Brown rice (BR) extract	48.96 ± 0.34%	54.14 ± 0.35%	[68]
	BR/Vanillin	99.32 ± 1.18%	86.48 ± 0.71%
	BR/Vanillyl alcohol	96.55 ± 0.12%	86.48 ± 0.71%
Biyun no.7 (Kidney bean)	Aqueous extract	1.659 ± 0.050 U/g DW	-	[69]
Rhus coriaria L.	Ethyl acetate sub-extract (leaves)	20.810 ± 0.747 μg/mL	26.993 ± 0.797 μg/mL	[70]
Melicope latifolia	Chloroform extract (bark)	1464.32 μg/mL		[71]
Arachis hypogaea	Ethanol extract (peanut seeds)	0.61 μg/mL	0.32 μg/mL	[72]
Backhousia citriodora	Essential oil	0.49 mg/μL	-	[73]
Rosmarinus officinalis	Essential oil of rosemary plus	0.45 mg/μL
Mentha piperita	Essential oil (leaf)	0.41 mg/μL
Origanum vulgare	Essential oil (leaf-phenol type)	0.41 mg/μL
Quercus variabilis Blume	Free polyphenol extract	5.25 ± 0.57 mg/mL	0.24 mg/mL	[74]
Quercus variabilis Blume	Bound polyphenol extract	1.37 ± 0.11 mg/mL	0.24 mg/mL	[74]
Centaurea pterocaula Trautv	Essential oil (aerial part)	79.66 ± 0.43 µg/mL	11.6 ± 0.18 µg/mL	[75]
Anchusa officinalis	Crude extract	954.16 ± 7.46 µg/mL	17.68 ± 1.24 µg/mL	[76]
Melilotus officinalis	Crude extract	1.32 ± 0.08 µg/mL	17.68 ± 1.24 µg/mL	[76]
Clausena indica	Hexane extract	1.37 ± 0.01 mg/mL	0.07 ± 0.00 mg/mL	[77]
Clausena indica	Ethyl acetate extract	8.56 ± 0.24 mg/mL	0.07 ± 0.00 mg/mL	[77]
Prosopis cineraria (L.)	n-Butanol fraction (pods)	22.01 ± 0.92 μg/mL	39.26 ± 2.19 μg/mL	[78]
Prosopis cineraria (L.)	Ethyl acetate fraction	28.23 ± 1.06 μg/mL	39.26 ± 2.19 μg/mL	[78]
Senna auriculata (L.) Roxb.	Methanolic extract (leaves)	49.45 μg/mL	-	[79]
Terfezia claveryi	Methanol extract	38.7 μg/mL	45.3 μg/mL	[80]
Rhododendron arboreum Sm.	Methanol extract	51.1%	-	[81]
Phragmites karka (Retz.)	Dichloromethane fraction (aerial part)	2.05 mg/mL	- -	[82]
Phragmites karka (Retz.)	n-Hexane fraction (aerial part)	2.08 mg/mL	- -	[82]
Morus nigra	Hexane fraction (leaves)	13.05 mg/mL	0 0.21 mg/mL	[83]
Salaria basilisca	Protein hydrolysates (peptide fraction F1)	71 μg/mL	14 μg/mL	[84]
Leucaena leucocephala (Lam.) De Wit	Ethanol extract (leaves)	288.01 μg/mL	252.59 μg/mL	[85]
Bergenia pacumbis	Methanol extract	14.03 ± 0.04 μg/mL	20.12 ± 0.12 μg/mL	[86]
Nonea obtusifolia (Wild.) DC.	Acetone extract	25.7 ± 0.08 μg/mL	28.18 ± 1.22 μg/mL	[87]
Morus alba Linn	Leaves	74.76 ± 6.76 μg/mL	35.34 ± 4.87 μg/mL	[88]
Phylanthus emblica L.	Methanolic extract (leaves)	98.37 ± 1.09%		[89]
Catunaregam spinosa	Dichloromethane fraction (bark)	77.17 ± 1.75 μg/mL	6.34 ± 0.07 μg/mL	[90]
Chenopodium album L.	Flavonoid fraction (aerial part)	122.18 ± 1.15 μg/mL	812.83 ± 1.07 μg/mL	[91]
Solanum virginianum	Aqueous extract (fruits)	54.12 ± 0.44–86.80 ± 0.27%	58.36 ± 0.30–88.24 ± 0.16%	[92]
Solanum virginianum	Ethanolic extract (fruits)	23.07 ± 0.47–81.61 ± 0.43%	58.36 ± 0.30–88.24 ± 0.16%	[92]
Eucalyptus globulus	Ethanol extract (Hexane defatted)	23.6 ± 1.2 μg/mL	5.2 ± 1.3 μg/mL	[93]
Eucalyptus globulus	Ethanol extract (non-defatted)	14.8 ± 1.2 μg/mL	5.2 ± 1.3 μg/mL	[93]
Maesobotrya dusenii Hutch.	Crude methanol extract	24 μg/mL	28 μg/mL	[94]
Veronica biloba	Aqueous extract	110.25 μg/mL	138.79 μg/mL	[95]
	Ethyl acetate extract	121.09 μg/mL
	Dichloromethane extract	123.68 μg/mL
Salvia lavandulifolia Vahl	Aqueous extract	0.99 ± 0.00 mg/mL	0.52 ± 0.01 mg/mL	[96]
Moringa oleifera	Methanolic crude extract (leaves)	65.6 ± 4.93%	-	[97]
Ziziphus mucronata	Acetone extract	0.62 mg/mL	0.42 mg/mL	[98]
Englerophytum magalismontanum	Methanol fraction (leaves)	10.76 ± 1.33 µg/mL	1.24 ± 1.64 µg/mL	[99]
Achyranthes aspera	Crude extract	97.60 ± 1.11 μg/mL	68.13 ± 0.46 μg/mL	[100]
Catharanthus roseus	Crude extract	94.05 ± 1.18 μg/mL	68.13 ± 0.46 μg/mL	[100]
Pterocarpus marsupium	Methanolic extract	158.663 ± 10.986 μg/mL	56.060 ± 4.465 μg/mL	[101]
Rubus corchorifolius L.	70% ethanolic extract (leaf tea)	1.26 ± 0.03 mg/mL	5.12 ± 0.42 mg/mL	[102]
	70% methanolic extract (leaf tea)	1.47 ± 0.05 mg/mL
	Aqueous extract (leaf tea)	4.39 ± 0.17 mg/mL
Sterculia nobilis Smith	Ethyl acetate fraction (pericarp)	13.550 ± 0.230 μg/mL	19.45 ± 0.26 μg/mL	[103]