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Dose proportionality assessment for steady-state PK parameters of cariprazine and metabolites. Dose proportionality assessment for steady-state pharmacokinetic parameters of cariprazine and metabolites. Pediatric patients 13–17 years old received 1.5 or 3 mg QD. Pediatric patients 10–12 years old received 0.75 or 1.5 mg QD. Pediatric patients 5–9 years old received 0.5 or 1.5 mg QD. CAR, cariprazine; DCAR, desmethyl cariprazine; DDCAR, didesmethyl cariprazine; QD, once daily.
