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LncRNAs can regulate the differentiation of B and T lineages from hematopoietic stem cells into mature cells, as well as the subsequent activation of these lymphocytes. HSC: Hematopoietic stem cell; CLP: common lymphoid progenitor; DN: double negative; DP: double positive; MZB: marginal zone B cell; CB: centroblast; CC: centrocyte.
