Skip to main content
. 2023 Aug 1;15(8):2071. doi: 10.3390/pharmaceutics15082071

Figure 17.

Figure 17

Generation of free radicals via US irradiation. (a) UV–vis spectra of ABTS+• produced after combining ABTS with various concentrations of AIPH@Cu-MOF. (b) Absorbance of ABTS+• at 736 nm in US-irradiated AIPH@Cu-MOF or Cu-MOF solutions. (c) Quantification of •OH produced by AIPH@Cu-MOF under normoxic or hypoxic conditions, as detected with APF. * p < 0.05. (d) Levels of intracellular free radicals in Panc02 cells determined by the DCFH-DA probe. (e) The cells were treated with AIPH@Cu-MOF (25 μg/mL), Cu-MOF (25 μg/mL), US (1.0 MHz, 0.5 W/cm2, 2 min, 50% duty cycle), or L-BSO (50 μg /mL). Scale bar: 20 μm. Reproduced with permission from ref. [109] (copyright 2021, Sun).