. 2023 Jul 31;15(8):1666. doi: 10.3390/v15081666

Table 1.

The inhibitory activity against SARS-CoV-2 (D614) PsV and cytotoxicity of phenothiazines in vitro ^a.

Compounds	IC₅₀ (μM)	CC₅₀ (μM)	SI ^b
Perphenazine	0.831 ± 0.120	18.120 ± 1.450	21.805
Acepromazine maleate	1.823 ± 0.230	93.300 ± 11.520	51.179
Fluphenazine decanoate	3.903 ± 1.090	61.570 ± 28.840	15.775
Prochlorperazine maleate	0.259 ± 0.048	85.160 ± 13.915	328.803
Alimemazine hemitartrate	0.477 ± 0.124	53.390 ± 10.945	111.929

^a Data are presented as mean ± SD of three independent experiments. ^b SI, selectivity index = CC₅₀/IC₅₀.