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. 2023 Jul 31;11(8):1977. doi: 10.3390/microorganisms11081977

Figure 1.

Figure 1

COG frequency across EV proteomes and functional classification. (a) Most COGs are found in only one EV proteome with decreasing number of COGs assigned to up to 12 EV proteins. (b) Approximately 200 COGs are each assigned to between 12 and 25 EV proteins. (c) A total of 55 COGs were assigned to at least 26 EV proteins; these most common COGs form the basis of the rest of the analysis (note that “hits” refer to proteins, which may be in the EV proteome of the same or different species; see Table 3 and Table 4 for the occurrence of these most common COGs across species). (d) Functional classification of COGs represented in all the EV proteomes analyzed (also see Table 2). The most common categories are C, E, G, M, P, and S.