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. 2023 Aug 6;31(9):101725. doi: 10.1016/j.jsps.2023.101725

Table 2.

Failure Mode Effect Analysis (FMEA).

Stage Potential Failure Modes Potential Effect(s) Causes O S D RPN 0 Recommendations/Actions taken New O New S New D RPN 1
1 Medication receipt from the main Drug store Medication without tracking barcode.
is not mapped in the system.
The medication batch is not found in the system.
-Manual process.
–No database.
9 6 7 378 -Full Mapping of the Health Information System (HIS).
System shall not allow expired medication dispensing.
3 3 5 45
2 Medication filling and arranged on shelves Manual process, no inventory or expiry track that is linked to Health Information System (HIS) –No database. 8 9 9 648 -Full Mapping on the HIS. 5 3 5 75
3 Prescriptions, including outsourced drugs, are unavailable. Service delay leads and inadequate time management. -Physical check by pharmaceutical professionals by going to the drug rack and checking it, then returning to the call to clarify with the prescriber.
-Manual method.
7 6 9 378 -Full HIS Mapping.
-Notify the clinician that substitutes are available
-Allow adding non-formulary medications into the system.
3 3 6 54
4 Multiple modifications on the same day of the patient's regimen A medication order is not dispensed.
Manual process.
-Wrong order that requires clarification/modification.
-Missed order that needs to be processed.
–No alert of duplication or interaction.
10 10 10 1000 -Introduce the clinical decision support that will follow the proper drug that is mapped 4 5 4 80
5 The patient's medical history shall be checked and reconciled at admission and discharge. If not done, the drug is not ordered or dispensed and could be missing. This causes a delay in service; the wrong medicine or dose maybe not be given.
-Hand-driven operation.
-The quantity available cannot be estimated
-Faulty order requiring explanation due to mismatch of diagnosis or improper reconciliation.
-Risk of missed order that needs to be processed.
-Prescribing the wrong medication based on the patient or relatives' feedback.
8 10 10 800 -Making a master list of all active and inactive medicines given to the patients throughout all visits.
-Computerize the reconciliation process much more than possible when it comes to -- Mandatory reconciliation upon admission and discharge.
-For nonformulary drugs: manual entries; are to be filled in the very same screen from a data set that allows additions on the HIS
5 9 5 225
6 Order Review -Medication mishaps
-There is no documentation of the prescriptions' appropriateness review or the procedure of checking order clarity and suitability.
-The system does not highlight interactions, duplications, and cross allergies (it depends on the pharmacist's manual review).
-When dispensing medications to patients, there is no routine alert for medications that always seem to be expired or near expiry.
-Dose calculations and numbers need to be corrected.
-Drops, ointment, and inhaler quantities are miscalculated.
-Clarification, if done, will be over the phone audibly with no records.
7 9 10 630 -Prescriptions must be filled out using drop-list options and minimizing free texts as much as possible.
–On the order entry stage, pharmacy clarification shall be documented HIS-wise.
-The order's status and progress are to be displayed.
-The system is designed to prevent off-readings and restrictions specified by the pharmacy and the assistance of the clinical decision-support system.
4 6 3 72
7 Order validation -The possibility of orders that are not processed or dispensed because they were missed
-If processing is delayed, the wrong medicine or dose may be given.
-The patient's medication may not be appropriate. 6 9 9 486 -The orders' status of processing is displayed.
-The system is designed to prevent off-readings and restrictions specified by the pharmacy and the assistance of the clinical decision-support system.
3 7 5 105
8 Preparation and dispensing - Adverse drug events may occur if there is a shortage of pharmacy stock, increased workload, and poor time management.
-Dispensing the incorrect drug that is not appropriate for the patient due to mode of administration, cross allergy, or even duplication of therapy errors on printed labels
-Inadequate double-checking by staff who alter labels manually
-Inconsistencies in stock on HIS displays
-Dispensing expired medications
-There needs to be detailed information on the label.
-Except for high-alert medications, there is no double-checking, and it is up to the employees involved.
-There needs to be traceable documentation of the medicine receipt.
-There is no retroactive verification and validation.
-There are no appropriateness review checkpoints.
-Printable labels cannot be edited.
-A shortage of Personnel.
–On the HIS, the label needs to be correctly mapped.
-Labels only include some of the information required by the labeling policy.
–No modification options for the label shall be printed on HIS.
7 7 10 490 -Ready batches/quantities for fast-moving pharmaceuticals.
-Allow label editing.
-Medicines identified by date and time and linked to a patient for tracking
-Actions are recorded and tracked electronically.
3 6 5 90
9 Health Information System (HIS) Medication incidents of the wrong patient or dose HIS screens have no fixed headers, causing mix-ups between patients' medications upon printing labels, especially in the manual issue. 10 10 10 1000 Standardize the screens to follow the standard pharmacy requirements per national and international elements.
mapping the drugs with templates and linking them to the clinical decision support system
8 7 7 392
Total RPN (RPN 0) 5810 Total New RPN (RPN 1) 1138