Skip to main content
. 2023 Aug 16;15(8):2149. doi: 10.3390/pharmaceutics15082149

Figure 2.

Figure 2

Identification and homing of Br-MSCs and exosomes and expression of the embryonic transcriptional factor of Br-MSCs (A–F). (A) TEM photomicrograph of exosomes; (B) flow cytometry of CD9 positive exosomes; (C) flow cytometry of CD63 positive exosomes; (D) detection of Br-MSCs, exosomes, Br-MSCs + EXOs in rat renal tissue at the end of the experiment via relative expression of human Gapdh mRNA at the end of the experiment after 12 weeks; (E) expression of Br-MSCs embryonic transcriptional factors (Nanog, OCT3/4, Sox2) compared with human mononuclear cell layer (MNC); (F) homing of exosomes in renal tissue of EXOs rats group 3rd day post-transplantation assayed by PKH-26, Scale bar 400 µm,; (G) % of the mean fluorescent intensity for positive and negative cell population for CD9 and CD63, Scale bar 400 µm, (H) representative photomicrograph for renal tissue of Nephro + CM group under florescent microscope showing negative florescent signal; *** p < 0.001, @,#,$,* Means bearing different superscripts were significantly different at p < 0.05.