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. 2023 Aug 21;11(8):1389. doi: 10.3390/vaccines11081389

Table 2.

Available evidence of relationship between indicators and measles CFR.

Published Literature Includes Randomized Controlled Trial with Significant Relationship Published Literature Supports Significant Observational Association Published Literature Supports Qualitative Association Published Literature with Non-Significant Evidence No Evidence Found in Published Literature
  • Vitamin A treatment

  • Average household size

  • Educational attainment

  • First-dose coverage of measles-containing vaccine (MCV1)

  • Human immunodeficiency virus (HIV) prevalence

  • Second-dose coverage of measles-containing vaccine (MCV2)

  • Stunting prevalence

  • Surrounding conflict

  • Travel time to major city or settlement

  • Travel time to nearest health care facility

  • Under-five mortality rate

  • Underweight prevalence

  • Vitamin A deficiency prevalence

  • General malnutrition (surrogate for wasting prevalence)

  • Level of health care available

  • Antibiotic use for measles-related pneumonia

  • Malaria prevalence

  • Percent living in urban settings

  • Pneumococcal conjugate vaccination coverage

  • Vitamin A supplementation

  • Access to intensive care unit

  • Ambient air pollution

  • De-worming frequency

  • Diarrheal disease prevalence

  • Health expenditure per capita

  • Human immunodeficiency virus (HIV) treatment/antiretroviral therapy (ART) prevalence

  • Lower respiratory infection prevalence

  • Maternal antibody dynamics

  • Maternal measles vaccination coverage

  • Oral rehydration solution for measles-related diarrhea

  • Population density

  • Pre-term birth prevalence *

  • Time to care seeking

  • Total fertility rate

  • Vaccine coverage equity

  • Vaccination efficacy

  • Vaccination schedule

Results from the literature review are summarized per indicator into one of five categories describing the level of evidence available from the published literature. * Evidence was found for an association but excluded for only having one study with significant evidence which had a small sample size across the entire body of evidence for this indicator.