Figure 2.

The mutation frequency was traced over time and registered for over one year. According to their trend, the 3D structures of N proteins presenting the most recurrent deletions were generated through RoseTTAFold, and images were created using Lasergene Protean 3D software from DNASTAR, Inc. The protein sequences were aligned to the Wuhan reference YP_009825061.1. The four deletions occurred in flexible link regions: (A) Pro207_Ala208del; (B) Ala208_Arg209del with a Glycine insertion; (C) Gly214_Gly215del; and (D) Glu31_Ser33del.