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18 SDoH factors (center) have a hierarchical relationship with the 5 SDoH domains define by HP-30 (left), both of which are knowledge driven. In contrast, the SDoH factors have a complex relationship with the SDoH subtypes (right) identified through machine learning (ML), reflecting how they co-occur in the real-world, and aligned with models such as the Dahlgren-Whitehead model (shown in Fig. 1).
