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(A,B) Nanosystem consisting of a calcium carbonate carrier as a delivery ICG [52,53]. (C) Combination therapy system of MnO2-assisted ICG to enhance photodynamic effect and suppression of immune checkpoint PD-L1 by siRNA [54]. (D) Nanoplatform for apoptosis induced by thermal effects and cytotoxicity generated by ICG molecules and drug activity of tumor-associated macrophages [55].
