Table 8.

Changes in impact on family at baseline, 3- months and 6-months.

Impact on Family Scale Questionnaire (n = 17) (Median [P25–P75])
	Baseline	3-Months Post Sapropterin	6-Months Post Sapropterin	Friedman Test (p Value < 0.05)
Financial Impact	7 [6–9]	8 [5–11]	11 [7–11]	0.062
Familial-Social Impact	15 [11–19]	19 [15–22]	21 [16–24]	0.002
Personal Strain	12 [9–15]	15 [9–17]	17 [11–20]	0.001
Mastery	8 [8–9]	8 [6–10]	7 [7–9]	0.861