ADC	Antibody-drug conjugates
ATCC	American Type Culture Collection
DAR	Drug-antibody-ratio
DM1	Mertansine
DTNB	5,5′-disthiobis 2-nitrobenzoic acid
DTT	Dithiothreitol
EDTA	Ethylenediaminetetraacetic acid
EMA	European Medicines Agency
FDA	Food and Drug Administration
GR50	Concentration at which growth rate = 0.5
GRI	Growth rate inhibition
HER2	Human epidermal growth factor receptor 2
IFP	Interstitial fluid pressure
mAb	Monoclonal antibody
MC	Maleimidocaproyl
MCC	4-(N-maleimidomethyl)cyclohexane-1-carboxylate
MMAE	Monomethyl auristatin E
nM	Nanomoles
PBS	Phosphate buffered saline
SE-HPLC	Size exclusion- high performance liquid chromatography
SMCC	Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate
SMCC-DM1	Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate Mertansine
Tmab	Trastuzumab
T-DM1	Trastuzumab emtansine
TNB	2-nitro-5-thiobenzoic acid
TROP-2	Tumour-associated calcium signal transducer 2
UV-Vis	Ultraviolet (UV)-visible spectroscopy
Val-Cit	Valine-Citrulline
VcMMAE	Valine-Citrulline Monomethyl auristatin E
WHO	World Health Organization