TABLE 2.

Comparison of different standardization/quantitation approaches applied on several HCV-positive plasma samples

Plasma sample no. and dilution	No. of copies with:
	Method A	Method B	Method C	Method D	Method E
100	7.0 × 105	3.3 × 105	4.8 × 105	6.0 × 105	5.1 × 105
1:10	NDa	4.0 × 104	6.2 × 104	5.1 × 104	9.5 × 104
1:100	ND	<2 × 103	<2 × 103	<2 × 103	<2 × 103
1:1000	ND	<2 × 103	<2 × 103	<2 × 103	<2 × 103
122	3.6 × 106	9.0 × 105	1.5 × 106	2.0 × 106	1.2 × 106
1:10	ND	1.2 × 105	1.8 × 105	1.8 × 105	2.7 × 105
1:100	ND	2.2 × 104	2.2 × 104	2.4 × 104	4.1 × 104
1:1000	ND	<2 × 103	<2 × 103	<2 × 103	<2 × 103
114	4.0 × 106	9.1 × 105	1.8 × 106	2.1 × 106	1.8 × 106
1:10	ND	2.4 × 105	3.5 × 105	4.2 × 105	4.5 × 105
1:100	ND	5.5 × 104	8.4 × 104	7.2 × 104	1.2 × 105
1:1000	ND	1.2 × 104	1.4 × 104	1.0 × 104	3.2 × 104
043	ND	>2 × 107	>2 × 107	>2 × 107	1.5 × 107
1:10	ND	4.3 × 106	1.0 × 107	8.3 × 106	5.1 × 106
1:100	ND	4.7 × 105	6.8 × 105	9.1 × 105	8.1 × 105
1:1000	ND	7.4 × 104	1.1 × 105	1.0 × 105	1.4 × 105
025	1.2 × 107	2.4 × 106	4.6 × 106	5.4 × 106	4.1 × 106
1:10	ND	4.7 × 105	7.8 × 105	9.7 × 105	7.2 × 105
1:100	ND	6.0 × 104	9.0 × 104	7.9 × 104	1.1 × 105
1:1000	ND	1.8 × 104	2.5 × 104	1.6 × 104	3.6 × 104

^aND, not determined.