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Evaluation of Select Chiral Ligands in the Annulation Reaction
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Reaction conditions: 49 (3.0 equiv), 50 (1.0 equiv), Pd2(dba)3 (5 mol%), ligand (20 mol%), CsF (10 equiv), H2O (9.0 equiv), MeCN (0.0125 M), 30 °C, 14 h.
Yield determined by an isolation experiment.
See SI, section F for details and crystallographic data.
