Table 2.
HRs and 95% CIs for small intestinal cancer risk in relation to lifestyle factors
| Small intestinal cancer (n = 160) | Adenocarcinoma (n = 51) | Carcinoid tumour (n = 62) | ||||
|---|---|---|---|---|---|---|
| Univariable model HR (95% CI) | Multivariable modela HR (95% CI) | Univariable model HR (95% CI) | Multivariable modela HR (95% CI) | Univariable model HR (95% CI) | Multivariable modela HR (95% CI) | |
| Alcohol (g/day) | ||||||
| T1 (0.35)b | Ref | Ref | Ref | Ref | Ref | Ref |
| T2 (5.49)b | 0.96 (0.65–1.43) | 0.84 (0.56–1.27) | 0.63 (0.31–1.29) | 0.54 (0.26–1.12) | 1.00 (0.54–1.84) | 0.86 (0.46–1.61) |
| T3 (22.86)b | 1.23 (0.85–1.79) | 1.02 (0.68–1.55) | 0.97 (0.51–1.82) | 0.79 (0.39–1.59) | 0.98 (0.54–1.81) | 0.91 (0.46–1.80) |
| p trend | 0.19 | 0.66 | 0.78 | 0.86 | 0.96 | 0.89 |
| Continuous (5 g/day) | 1.04 (1.00–1.08) | 1.03 (0.98–1.07) | 1.03 (0.96–1.11) | 1.02 (0.94–1.11) | 0.99 (0.91–1.07) | 0.98 (0.89–1.08) |
| Smoking | ||||||
| Never | Ref | Ref | Ref | Ref | Ref | Ref |
| Former | 1.32 (0.91–1.92) | 1.03 (0.70–1.52) | 1.19 (0.61–2.31) | 0.98 (0.50–1.95) | 1.28 (0.69–2.35) | 1.01 (0.54–1.89) |
| Current | 1.77 (1.21–2.60) | 1.29 (0.87–1.92) | 1.82 (0.94–3.55) | 1.47 (0.74–2.94) | 1.76 (0.95–3.29) | 1.30 (0.68–2.46) |
| Physical activity | ||||||
| Inactive | Ref | Ref | Ref | Ref | Ref | Ref |
| Moderately inactive | 0.94 (0.62–1.42) | 0.81 (0.53–1.24) | 1.12 (0.52–2.41) | 0.99 (0.45–2.16) | 0.91 (0.47–1.79) | 0.77 (0.39–1.53) |
| Moderately active | 0.91 (0.58–1.45) | 0.70 (0.44–1.14) | 1.08 (0.46–2.53) | 0.92 (0.38–2.22) | 1.20 (0.60–2.41) | 0.86 (0.41–1.79) |
| Active | 1.09 (0.67–1.75) | 0.78 (0.47–1.29) | 1.61 (0.70–3.72) | 1.15 (0.47–2.78) | 0.73 (0.31–1.73) | 0.57 (0.23–1.40) |
HR hazard ratio, 95% CI 95% confidence interval, Ref reference category
aStratified by age, sex and country
bMedian value of tertile