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. 2023 Aug 26;10:570. doi: 10.1038/s41597-023-02482-8

Table 4.

Image-level cancer cell detection performance of our method on the test split.

Detection Alogrithm Setting Detection stage Full pipeline (ω = 1) Full pipeline (ω = 0.7)
AP50 F1 AP50 F1 AP50 F1
Faster R-CNN29 Brightfield 43.1 ± 0.6 50.3 ± 0.3 50.6 ± 0.2 54.1 ± 0.2 52.2 ± 0.2 55.4 ± 0.3
Brightfield + Hoechst 45.5 ± 0.7 52.2 ± 0.3 56.5 ± 0.5 57.8 ± 0.4 57.7 ± 0.3 59.3 ± 0.3
Brightfield + Fluorescence 86.6 ± 0.3 87.3 ± 0.1 86.7 ± 0.3 86.2 ± 0.2 89.2 ± 0.3 87.8 ± 0.1
FCOS39 Brightfield 46.7 ± 0.2 51.5 ± 0.2 51.4 ± 0.1 54.9 ± 0.3 52.4 ± 0.1 55.3 ± 0.3
Brightfield + Hoechst 48.2 ± 0.6 52.8 ± 0.2 57.7 ± 0.4 58.8 ± 0.4 58.7 ± 0.3 59.2 ± 0.8
Brightfield + Fluorescence 89.8 ± 0.3 86.0 ± 0.1 88.4 ± 0.4 85.2 ± 0.1 90.8± 0.2 86.7 ± 0.1
DINO40 Brightfield 43.6 ± 0.3 49.7 ± 0.2 52.1 ± 0.2 54.4 ± 0.3 52.9 ± 0.1 55.1 ± 0.3
Brightfield + Hoechst 45.1 ± 0.4 50.4 ± 0.3 58.3 ± 0.3 57.8 ± 0.5 58.9 ± 0.2 58.7 ± 0.4
Brightfield + Fluorescence 91.0 ± 0.3 86.7 ± 0.5 89.0 ± 0.1 85.9 ± 0.2 91.7 ± 0.3 87.5 ± 0.3