Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 26;14(8):566. doi: 10.1038/s41419-023-06091-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — A USP14 protein levels in livers of shNC or shUSP14 adenovirus-treated mice. B, C GTT and ITT analysis of mice 5 weeks after shNC or shUSP14 adenovirus injection (n = 12). AUC, area under the curve. D Effect of shNC or shUSP14 adenovirus injection on eWAT weight and LW/BW ratios in mice (n = 5). E–G Effect of shNC or shUSP14 adenovirus injection on serum or liver TG and TC levels and serum AST and ALT levels in mice (n = 5). H H&E staining and adipocyte counts of eWAT (n = 5). I H&E staining, oil red O staining, and PSR staining from the livers of mice in each group (n = 5). Scale bar, 50 μm. J, K NAS score and relative PSR area from each group of mice. L Expression of inflammatory and fibrotic genes in the liver of each group of mice (n = 5). M Expression of lipid metabolism-related proteins, inflammation-related proteins, fibrosis-related proteins, and insulin sensitivity-related proteins in the liver of mice in each group. * P < 0.05 for the HFD-shNC compared to the HFD-shUSP14 group; ** P < 0.01 for the HFD-shNC compared to the HFD- shUSP14 group. NS not significant.