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. Author manuscript; available in PMC: 2023 Aug 27.
Published in final edited form as: J Am Coll Cardiol. 2022 Aug 30;80(9):873–883. doi: 10.1016/j.jacc.2022.05.049

Figure 1.

Figure 1.

Continuous association between GPSCAD and modes of death. Results of the association between continuous GPSCAD and SAD is shown on the left and non-SAD on the right. The distribution of scores The black line represents the hazard ratio and the red dotted lines represent the 95% confidence interval. The multivariable-adjusted spline model demonstrate a non-linear association with significant SAD risk elevation above a GPSCAD score of 1.46. This was not seen for non-SAD risk. Please refer to the Statistical Analysis section for definitions of variables adjusted for in the model. GPSCAD decile = genome-wide polygenic score for coronary artery disease, non-SAD = non-sudden and non-arrhythmic death, SAD = sudden and/or arrhythmic death.