Table 1.
Demographics and Clinical Characteristics of the Subgroup According to Functional Outcome at Discharge
| Good Functional Outcome | Poor Functional Outcome | P values | |
|---|---|---|---|
| N=667 | N=194 | ||
| Demographic | |||
| Age, years, (median [IQR]) | 64[54,71] | 66[58,73] | P=0.019 |
| Age, years, female (median [IQR]) | 68[60,75] | 71[63.77] | P=0.046 |
| Male, n (%) | 441(66.1%) | 111(57.2%) | P=0.027 |
| Smoker, n (%) | 235(35.2%) | 62(32.0%) | P=0.440 |
| Alcohol user, n (%) | 205(30.7%) | 47(24.2%) | P=0.089 |
| Clinical features, (median [IQR]) | |||
| Hospitalization days, d | 11[9,13] | 12[10,15] | P<0.001 |
| SBP, mmHg | 150[136,164] | 151[138,162] | P=0.496 |
| DBP, mmHg | 90[81,99] | 89[82,100] | P=0.892 |
| Admission NIHSS score | 2[1,4] | 6[4,11] | P<0.001 |
| Laboratory data, (median [IQR]) | |||
| TC, mmol/L | 4.56[3.83,5.33] | 4.42[3.72,5.36] | P=0.426 |
| TG, mmol/L | 1.33[0.96,1.86] | 1.20[0.91,1.66] | P=0.017 |
| HDL-C, mmol/L | 0.99[0.84,1.14] | 0.98[0.81,1.19] | P=0.904 |
| LDL-C, mmol/L | 2.87[2.35,3.45] | 2.83[2.32,3.49] | P=0.961 |
| GLU, mmol/L | 5.40[4.82,6.86] | 5.63[4.84,7.38] | P=0.445 |
| NLR | 2.50[1.88,3.60] | 3.34[2.42,5.38] | P<0.001 |
| PLR | 129.38[101.03,176.10] | 150.45[112.67,209.17] | P<0.001 |
| LMR | 4.00[3.00,5.25] | 3.34[2.26,4.50] | P<0.001 |
| SIRI | 1.02[0.74,1.62] | 1.60[0.92,2.65] | P<0.001 |
| Medical history, n (%) | |||
| Hypertension | 460(69.0%) | 133(68.6%) | P=0.930 |
| Diabetes | 186(27.9%) | 59(30.4%) | P=0.527 |
| Stroke | 186(27.9%) | 73(37.6%) | P=0.010 |
| Atrial fibrillation | 29(4.3%) | 12(6.2%) | P=0.337 |
| Coronary heart disease | 62(9.3%) | 21(10.8%) | P=0.580 |
| Medication use history, n (%) | |||
| Lipid lowering drugs | 95(14.2%) | 29(14.9%) | P=0.817 |
| Hypoglycemic drugs | 132(19.8%) | 49(25.3%) | P=0.109 |
| Antihypertensive drugs | 292(43.8%) | 82(42.3%) | P=0.742 |
| Antiplatelet drugs | 126(18.9%) | 39(20.1%) | P=0.756 |
| Thrombolysis | 27(4.0%) | 14(7.2%) | P=0.068 |
| TOAST classification, n (%) | P<0.001 | ||
| Large-artery atherosclerosis | 294(44.1%) | 129(66.5%) | |
| Small-artery occlusion | 346(51.9%) | 54(27.8%) | |
| Cardio-embolism | 19(2.8%) | 8(4.1%) | |
| Other etiology | 7(1.0%) | 3(1.5%) | |
| Undetermined etiology | 1(0.1%) | 0(0.0%) |
Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institute of Health Stroke Scale; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; GLU, Plasma glucose; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio; SIRI, systemic inflammation response index.