Table 4.
Multivariate Logistic Regression Analysis According to Quartiles of NLR, PLR, LMR, and SIRI
| Clinical Outcome | NLR | P values | |||
|---|---|---|---|---|---|
| Q1 (<1.96) N=214 | Q2 (1.96–2.63) N=216 | Q3 (2.64–3.99) N=215 | Q4 (≥4.00) n=216 | ||
| Poor functional outcome | |||||
| Cases, n (%) | 25(11.7%) | 41(19.0%) | 52(24.2%) | 76(35.2%) | P<0.001 |
| Model 1 | 1.00 | 1.538(0.841–2.812) | 2.269(1.273–4.047) | 2.607(1.463–4.644) | |
| Model 2 | 1.00 | 1.463(0.795–2.694) | 2.197(1.227–3.934) | 2.495(1.394–4.466) | |
| PLR | |||||
| Clinical outcome | Q1 (<103.19) N=215 | Q2 (103.19–134.96) N=215 | Q3 (134.97–180.92) N=216 | Q4 (≥180.93) n=215 | |
| Poor functional outcome | |||||
| Cases, n (%) | 35(16.3%) | 44(20.5%) | 52(24.1%) | 63(29.3%) | P=0.010 |
| Model 1 | 1.00 | 1.429(0.820–2.492) | 1.706(0.975–2.985) | 1.962(1.149–3.351) | |
| Model 2 | 1.00 | 1.421(0.811–2.491) | 1.694(0.963–2.980) | 1.959(1.138–3.373) | |
| LMR | |||||
| Clinical outcome | Q1 (<2.90) N=213 | Q2 (2.90–3.79) N=209 | Q3 (3.80–4.99) N=198 | Q4 (≥5.00) n=241 | |
| Poor functional outcome | |||||
| Cases, n (%) | 73(34.3%) | 48(23.0%) | 41(20.7%) | 32(13.3%) | P<0.001 |
| Model 1 | 2.384(1.386–4.098) | 1.651(0.946–2.882) | 1.607(0.912–2.833) | 1.00 | |
| Model 2 | 2.300(1.331–3.975) | 1.539(0.876–2.704) | 1.509(0.850–2.679) | 1.00 | |
| SIRI | |||||
| Clinical outcome | Q1 (<0.77) N=214 | Q2 (0.77–1.11) N=213 | Q3 (1.12–1.79) N=214 | Q4 (≥1.80) n=220 | |
| Poor functional outcome | |||||
| Cases, n (%) | 35(16.4%) | 28(13.1%) | 49(22.9%) | 82(37.3%) | P<0.001 |
| Model 1 | 1.00 | 0.730(0.401–1.331) | 1.359(0.791–2.337) | 1.932(1.150–3.248) | |
| Model 2 | 1.00 | 0.682(0.372–1.251) | 1.304(0.754–2.255) | 1.866(1.106–3.146) | |
Notes: Model 1: adjusted for age, sex, length of hospital stay, NIHSS score at admission, TOAST classification and stroke history.Model 2: further adjusted for TG, smoking, drinking, medical history (hypertension, diabetes, atrial fibrillation), thrombolysis and glucose-lowering drugs.
Abbreviations: NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio; SIRI, systemic inflammation response index; NIHSS, National Institute of Health Stroke Scale; TG triglyceride.