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. 2022 Jul 2;13(3):435–445. doi: 10.34172/apb.2023.047

Table 1. MicroRNAs are involved in the cancer-causing process .

Type of cancer microRNA Target gene Role in cancer Reference
Liver cancer miR-503 VEGF-A and FGF2 Inhibition of angiogenesis 65
Ovarian cancer miR-125b HIF-1a, VEGF, HER2, HER3 Inhibition of angiogenesis 66
Bladder cancer miR-200 family (miR-200a/200b/200c/141/429) ZEB EMT/MET process 67
Colorectal cancer miR-34a Snail, ZNF281, IL-6R EMT process 68
Breast cancer miR-335 SOX4, TNC migration and invasion 69
Gastric cancer MiR-503 Notch and IGF1R EMT process 70
Non-small cell lung cancer MiR-194 BMI-1 migration and invasion 70
Glioma cancer MiR-128 E2F3a cell growth 71

EMT, Epithelial-mesenchymal transition; MET, mesenchymal-epithelial transition.